M.Sc. Assel Berikkara

Research focus

• native mass spectrometry (MS) and single-particle imaging of coronaviral non-structural proteins (nsps)
• structural organization, spatial arrangement, and topology of nsps under native conditions

Methods & approaches

• application of multiple ion-activation and fragmentation techniques on the hybrid Orbitrap–Omnitrap platform
• comparative evaluation of electron-, photon-, and collision-based dissociation methods for native MS of nsps
• integration of native MS with single-particle imaging strategies

Expertise

• mammalian and bacterial protein expression systems
• native mass spectrometry
• multimodal ion-activation and fragmentation workflows