Main research topics

  • NMR studies of protein-carbohydrate interactions (monoclonal antibodies, lectins, selectins, siglecs, glycosyltransferases)
  • NMR studies of ligand binding to native viruses and viral coat proteins. Design of novel entry inhibitors
  • Recombinant production of isotope labeled glycosyltransferases for NMR spectroscopic experiments
  • Studies of thermodynamic and kinetic aspects of carbohydrate-protein recognition reactions using NMR, surface plasmon resonance and microcalorimetry
  • structural and biophysical characterization of skin matrix proteins involved in autoimmunity